Bacillus clausii belong to the group of bacteria with the ability to form spores. This helps the bacteria resist harsh conditions that may alter its efficacy. This is an advantage over the other common probiotics, such as Lactobacillus spp, which are non-spore forming¹³.
Aside from resisting heat, stomach and intestinal acids, Bacillus clausii spores can withstand the effect of antibiotics.
1.The spores protect Bacillus clausii from the killing effects of the antibiotics⁵⁵
2. The antibiotic resistance of the Bacillus clausii cannot be transferred to any other organism⁴⁰.