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Get prescription-strength arthritis pain relief without a prescription.

Aspercreme® Arthritis Pain Relief Gel with diclofenac targets pain directly at the source to reduce inflammation and help relieve arthritis pain.

Full prescription strength

Reduces inflammation

Targets pain directly at the source

Use as directed.

Sizes: 50g tube | 100g tube | 150g tube

Where to Buy



    • for the temporary relief of arthritis pain ONLY in the following areas:
      • hand, wrist, elbow (upper body areas)
      • foot, ankle, knee (lower body areas)
    • this product may take up to 7 days to work for arthritis pain; it is not for immediate relief. If no pain relief in 7 days, stop use.

    Use up to 21 days unless directed by your doctor.

    Not for strains, sprains, bruises, or sports injuries. This product has not been shown to work for these types of injuries.


    For your arthritis pain:

    Use 4 times per day every day

    Do not use on more than 2 body areas at the

    same time


    Per Dose

    Use ENCLOSED DOSING CARD to measure

    a dose

    For each upper body area (hand, wrist, or

    elbow) – Squeeze out 2.25 inches (2 grams)

    For each lower body area (foot, ankle, or knee)

    – Squeeze out 4.5 inches (4 grams)

    Read the User Guide for complete instructions:
    • use only as directed
    • do not use more than directed or for longer than directed
    • apply only to clean, dry skin that does not have any cuts, open wounds, infections, or rashes
    • do not apply in same area as any other product
    • do not apply with external heat such as heating pad
    • do not apply a bandage over the treated area
    • store ENCLOSED DOSING CARD with your Aspercreme® Arthritis Pain Relief Gel. The dosing card is re-usable.

    For external use only

    Allergy alert: Diclofenac may cause a severe allergic reaction, especially in people allergic to aspirin.

    Symptoms may include:
    • hives
    • asthma (wheezing)
    • skin reddening
    • blisters
    • facial swelling
    • shock
    • rash
    If an allergic reaction occurs, stop use and seek medical help right away. Liver warning: This product contains diclofenac. Liver damage may occur if you apply
    • more or for a longer time than directed
    • when using other drugs containing diclofenac
    Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is small but higher if you
    • are age 60 or older
    • have had stomach ulcers or bleeding problems
    • take a blood thinning (anticoagulant) or steroid drug
    • take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
    • have 3 or more alcoholic drinks every day while using this product
    • apply more or for longer than directed
    Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed. Do not use
    • if you have ever had an allergic reaction to any other pain reliever or to a fever reducer
    • for strains, sprains, bruises, or sports injuries. This product has not been shown to work for these types of injuries.
    • right before or after heart surgery
    • on more than 2 body areas at the same time
    • in the eyes, nose, or mouth
    Ask a doctor before use if
    • you have problems or serious side effects from taking pain relievers or fever reducers
    • stomach bleeding warning applies to you
    • you have a history of stomach problems, such as heartburn
    • you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke
    • you are taking a diuretic
    • you are under age 18 years. It is not known if this drug works or is safe in children under age 18 years.
    Ask a doctor or pharmacist before use if you are
    • under a doctor’s care for any serious condition
    • taking any other drug
    When using this product
    • avoid contact with eyes, nose, or mouth
    • if eye contact occurs, rinse thoroughly with water
    Stop use and ask a doctor if
    • pain gets worse or lasts more than 21 days
    • redness or swelling is present in the painful area
    • fever occurs
    • skin irritation occurs
    • any new symptoms appear. These could be signs of a serious condition.
    • you experience any of the following signs of stomach bleeding:
      • feel faint
      • have bloody or black stools
      • vomit blood
      • have stomach pain that does not get better
    • you have symptoms of heart problems or stroke:
      • chest pain
      • trouble breathing
      • leg swelling
      • weakness in one part or side of body
      • slurred speech

    If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use this product during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222).

    • store at 20-25°C (68-77°F). Keep from freezing.
    • read all product information before using. Keep the dosing card, this carton, and accompanying User Guide for important information.

    Keep carton as it contains important information.


A woman rubs cream into her hands.

    Diclofenac sodium

    Diclofenac sodium is a topical non-steroidal anti-inflammatory drug (NSAID) that helps ease arthritis pain.

    carbomer homopolymer Type C, cocoyl caprylocaprate, fragrance, isopropyl alcohol, mineral oil, polyoxyl 20 cetostearyl ether, propylene glycol, purified water, strong ammonia solution


  • You may be able to use your HSA and FSA tax-preferred savings accounts to purchase certain Aspercreme® OTC products. The passage of the CARES Act by Congress includes provisions to restore OTC eligibility under tax-preferred HSA and FSA accounts. Plan details vary, so save your receipt and check with your benefits or health provider for eligibility.

  • Do not use a heating pad or ice pack while using Aspercreme® products.

  • Aspercreme® Arthritis Pain Relief Gel is used for the temporary relief of arthritis pain in your upper (hands, wrists, elbows) and lower (knees, feet, ankles) body areas.

  • Please reach out to our Consumer Affairs Team at 866-844-2798 or visit to request a replacement dosing card.

  • Please consult your doctor if you are pregnant or nursing before using Aspercreme® products.

  • Aspercreme® products should not be used after they expire. Check the packaging for the expiration date.

  • Do not use more than one Aspercreme® product or any other medication at the same time. Use all products only as directed. We recommend you speak to your doctor if you have additional questions.

  • Aspercreme® Arthritis Pain Relief Gel contains diclofenac, which is an NSAID.

  • We do not test Aspercreme® Arthritis Pain Relief Gel for use on animals. Please use only as directed.

  • Ask a doctor before using this product on children aged under 18 years.

  • Aspercreme® products can be purchased without a prescription. Please visit the "Where to buy" page to find your closest retailer.